Lynch Syndrome - Podcast
Linda is aged 66 years, she has 3 children and one grandchild. Linda presented about a year ago with post-menopausal bleeding and was referred straight away. She was diagnosed with endometrial cancer and has had successful treatment.
Linda tells us that her brother was recently diagnosed with colorectal cancer at the age of 48. There’s no other family history of colorectal cancer, but Linda is telling us that her mother died of ovarian cancer aged 76 and her uncle had bladder cancer.
This is a narrative often described by patients. And it begs the question:
Lynch Syndrome is known as hereditary non-polyposis colorectal cancer and it is the most common inherited syndrome associated with colorectal cancer (accounts for 5% of colorectal cancers) and also associated with non-colonic cancers, especially endometrial, ovarian, renal tract, hepato-biliary and stomach cancers.
Listen to our podcast on Lynch Syndrome to find out more:
References
Lancet 2020;395:1817 & NICE 2020 NG151 & NICE DG27 & NEJM2018;379:764
The Medcast medical education team is a group of highly experienced, practicing GPs, health professionals and medical writers.
Become a member and get unlimited access to 100s of hours of premium education.
Learn moreAnthony is a retired engineer, who is compliant with his COPD and diabetes management but has been struggling with frequent exacerbations of his COPD.
Whilst no longer considered a public health emergency, the significant, long-term impacts of Covid-19 continue to be felt with children’s mental health arguably one of the great impacts of the pandemic.
Your next patient is Frankie, a 5 year old girl, who is brought in by her mother Nora. Frankie has been unwell for the past 48 hours with fever, sore throat and headache. The previous day Nora noticed a rash over Frankie’s neck and chest which has since spread over the rest of her body.