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Lynch Syndrome - Podcast

09 February 2021 - Medcast Medical Education Team

Linda is aged 66 years, she has 3 children and one grandchild. Linda presented about a year ago with post-menopausal bleeding and was referred straight away. She was diagnosed with endometrial cancer and has had successful treatment.

Linda tells us that her brother was recently diagnosed with colorectal cancer at the age of 48. There’s no other family history of colorectal cancer, but Linda is telling us that her mother died of ovarian cancer aged 76 and her uncle had bladder cancer.

This is a narrative often described by patients. And it begs the question:

Are Linda and her family just unlucky, or do we need to think proactively and consider if Linda could have Lynch Syndrome?


Lynch Syndrome is known as hereditary non-polyposis colorectal cancer and it is the most common inherited syndrome associated with colorectal cancer (accounts for 5% of colorectal cancers) and also associated with non-colonic cancers, especially endometrial, ovarian, renal tract, hepato-biliary and stomach cancers.

Listen to our podcast on Lynch Syndrome to find out more:



Lancet 2020;395:1817 & NICE 2020 NG151 & NICE DG27 & NEJM2018;379:764


Medcast Medical Education Team
Medcast Medical Education Team

The Medcast medical education team is a group of highly experienced, practicing GPs, health professionals and medical writers.

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