Crohn’s disease - clinical fact sheet and MCQ
Overview
Crohn’s disease (CD) is a chronic, immune-mediated inflammatory bowel disease (IBD) characterised by relapsing inflammation that can involve any segment of the gastrointestinal (GI) tract, often discontinuously. It affects all layers of the intestinal wall and is associated with systemic and extra-intestinal manifestations, such as arthropathy, pyoderma gangrenosum, erythema nodosum, uveitis, and hepatobiliary complications.1
Aetiology involves genetic predisposition (up to 30% risk), with environmental triggers such as a Western diet, the patient’s gut microbiome, medications, and smoking playing significant roles.1,2
CD is most prevalent among individuals between 15 to 25 years of age2 with an estimated 306 per 100,000 people affected in Australia.3 The incidence of CD is increasing worldwide.2
Diagnosis of Crohn’s disease
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