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Antidepressant deprescribing

Support for health professionals to complement the Antidepressant Deprescribing Plan. Includes information on tapering options and distinguishing withdrawal symptoms from relapse.

To help us understand the impact of our resources, please let us know if you are downloading to use with a patient or for general educational purposes.

QHub antidepressants deprescribing clinical guide snapshot

 

  1. The Maudsley Deprescribing Guidelines: Antidepressants, Benzodiazepines, Gabapentinoids and Z-drugs https://www.wiley.com/en-us/The+Maudsley+Deprescribing+Guidelines%3A+Antidepressants%2C+Benzodiazepines%2C+Gabapentinoids+and+Z-drugs-p-9781119823025 

  2. Royal Australian and New Zealand College of Psychiatrists. Mood disorders: clinical practice guidelines. 2020 https://www.ranzcp.org 

  3. Therapeutic Guidelines https://tgldcdp.tg.org.au/viewTopic?etgAccess=true&guidelinePage=Psychotropic&topicfile=major-depression 

  4. Royal College of Psychiatrists (UK). Stopping antidepressants, 2021 https://www.rcpsych.ac.uk/mental-health/treatments-and-wellbeing/stopping-antidepressants 

  5. AMH Aged Care Companion, 2024 https://agedcare.amh.net.au/chapters/neurological-mental-health/depression 

  6. Van Leeuwen E. Cochrane Database Syst Rev. 2021; 2021(4): CD013495.

Related resources
Conversation Starters
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Useful verbatims to support what are often challenging conversations with patients about antidepressant tapering.

Care Plan
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A shared decision-making tool to support consumers thinking about tapering or stopping their antidepressant.